← Back to all articles
PTSDPubMed VerifiedOpen Access

Exploring the therapeutic effects of psychedelics administered to military veterans in naturalistic retreat settings

Calnan M, Blest-Hopley G, Busch C, Adams M, Ruffell SGD, Piper T, Roseman L, Kettner H, Carhart-Harris R

Brain and Behavior (2025)

Prospective observational
Abstract

First study investigating psychedelic retreats as holistic therapy for veterans' mental health and community reintegration. 58 veterans attended psilocybin or ayahuasca retreats. Significant improvements found for all eight outcomes post-retreat, with greatest improvements for depression (PHQ-9; 29.1%) and PTSD (PCL-5; 26.1%). Ayahuasca retreats demonstrated greater improvements in PTSD scores. Veterans with more severe symptoms benefited most.

Participants58
Study TypeProspective observational
veteransPTSDpsilocybinretreatsmilitarydepression
DOI: 10.1002/brb3.70660View on PubMed

Related Articles

PTSD

Prevalence and therapeutic impact of adverse life event reexperiencing under ceremonial ayahuasca

Weiss B, Wingert A et al.

Scientific Reports, 2023
PTSD

Ayahuasca ceremony in the treatment of a patient with PTSD: a case report

Coelho HF, Oliveira RD et al.

Journal of Psychedelic Studies, 2021
PTSD

Hypothesis: The psychedelic ayahuasca heals traumatic memories via a sigma 1 receptor-mediated epigenetic-mnemonic process

Inserra A

Frontiers in Pharmacology, 2018
Reviews

The Therapeutic Use of Ayahuasca

Labate BC, Cavnar C

Springer, 2014