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PharmacologyPubMed VerifiedOpen Access

Neurobiological research on N,N-dimethyltryptamine (DMT) and its potentiation by monoamine oxidase (MAO) inhibition: from ayahuasca to synthetic combinations of DMT and MAO inhibitors

Egger K, Aicher HD, Cumming P, Scheidegger M

Cellular and Molecular Life Sciences (2024)

Comprehensive review
Abstract

Comprehensive review of DMT neurobiology from ayahuasca to synthetic MAO inhibitor combinations. Covers receptor pharmacology, neuroimaging, electrophysiology, and clinical data. Discusses the shift from botanical ayahuasca to standardized pharmaceutical-grade DMT/harmine formulations for clinical trials.

Citations10
Study TypeComprehensive review
DMTMAO inhibitionneurobiologicalpharmacologysynthetic formulations
DOI: 10.1007/s00018-024-05353-6View on PubMed

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