PharmacologyPubMed VerifiedOpen Access
N,N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca regulates adult neurogenesis in vitro and in vivo
Translational Psychiatry (2020)
Preclinical / in vivo
Abstract
Showed DMT promotes neurogenesis both in vitro (neural progenitor cells) and in vivo (mouse hippocampus). DMT-treated mice showed improved performance in memory tasks. Suggests neuroplasticity as a therapeutic mechanism.
Citations180
Study TypePreclinical / in vivo