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PharmacologyPubMed VerifiedOpen Access

N,N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca regulates adult neurogenesis in vitro and in vivo

Morales-Garcia JA, Calleja-Conde J, Lopez-Moreno JA, Alonso-Gil S, Sanz-SanCristobal M, Riba J, Perez-Castillo A

Translational Psychiatry (2020)

Preclinical / in vivo
Abstract

Showed DMT promotes neurogenesis both in vitro (neural progenitor cells) and in vivo (mouse hippocampus). DMT-treated mice showed improved performance in memory tasks. Suggests neuroplasticity as a therapeutic mechanism.

Citations180
Study TypePreclinical / in vivo
neurogenesisDMThippocampusneuroplasticitypreclinical
DOI: 10.1038/s41398-020-01011-0View on PubMed

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