Toxicokinetics and toxicodynamics of ayahuasca alkaloids N,N-dimethyltryptamine (DMT), harmine, harmaline and tetrahydroharmine: clinical and forensic impact

Thorough mechanistic review of how each ayahuasca alkaloid is absorbed, distributed, and metabolized. Explains how harmala MAO-A inhibition enables oral DMT bioavailability and details clinical and forensic implications of the pharmacokinetic interaction.