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Clinical Trials
DOI Resolved

Combined DMT-harmine formulation reduces negative self-referential emotions during social self-evaluation: a randomized placebo-controlled trial in healthy volunteers

Aicher HD, Dornbierer J, Caflisch L et al.
Psychopharmacology, 2026
Randomized Controlled Trial
Clinical Trials
DOI Resolved

Global increases in brain glucose metabolism following acute N,N-dimethyltryptamine and harmine administration in healthy volunteers: A randomised [18F]FDG-PET study

Egger K, Bozsak R, Aicher HD et al.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2026
Neuroimaging study
Pharmacology
PubMed Verified

DMT and harmala alkaloids: an exploratory study of oral Acacia based formulations in healthy volunteers

Bonomo YA, Norman AF, Collins L et al.
Frontiers in Psychiatry, 2025
Open Access
Open-label crossover
Clinical Trials
PubMed Verified

Acute experiences and persisting psychological effects associated with an encapsulated DMT-harmala alkaloid combination: results of a phase 1 study

Perkins D, Halman A, Urokohara A et al.
Scientific Reports, 2025
Open Access
Phase 1 trial
Pharmacology
PubMed Verified

Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: a factorial dose-escalation study

Egger K, Jareno Redondo J, Mueller J et al.
Biomedicine & Pharmacotherapy, 2025
5 citationsOpen Access
Randomized controlled trial
Pharmacology
PubMed Verified

Bringing ayahuasca to the clinical research laboratory

Riba J, Barbanoj MJ
Journal of Psychoactive Drugs, 2005
150 citations
Methodological review