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8 results for “sigma-1”
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Pharmacology
NewPubMed Verified

Why N,N-dimethyltryptamine matters: unique features and therapeutic potential beyond classical psychedelics

Chaves C, Dos Santos RG, Dursun SM et al.
Frontiers in Psychiatry, 2024
5 citationsOpen Access
Review
Pharmacology
NewPubMed Verified

Molecular pathways of the therapeutic effects of ayahuasca, a botanical psychedelic and potential rapid-acting antidepressant

Rossi GN, Guerra LTL, Baker GB et al.
Biomolecules, 2022
35 citationsOpen Access
Narrative review
Psychology
NewPubMed Verified

Ceremonial ayahuasca in Amazonian retreats - Mental health and epigenetic outcomes from a six-month naturalistic study

Ruffell SGD, Netzband N, Tsang W et al.
Frontiers in Psychiatry, 2021
40 citationsOpen Access
Prospective observational
PTSD
NewPubMed Verified

Hypothesis: The psychedelic ayahuasca heals traumatic memories via a sigma 1 receptor-mediated epigenetic-mnemonic process

Inserra A
Frontiers in Pharmacology, 2018
80 citationsOpen Access
Theoretical / hypothesis
Reviews
NewPubMed Verified

The therapeutic potentials of ayahuasca: possible effects against various diseases of civilization

Frecska E, Bokor P, Winkelman M
Frontiers in Pharmacology, 2016
250 citationsOpen Access
Narrative review
Pharmacology
NewPubMed Verified

The endogenous hallucinogen and trace amine N,N-dimethyltryptamine displays potent protective effects against hypoxia via sigma-1 receptor activation in human primary iPSC-derived cortical neurons and microglia-like immune cells

Szabo A, Kovacs A, Riba J et al.
Frontiers in Neuroscience, 2016
200 citationsOpen Access
Preclinical in vitro