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Depression & Mood
DOI Resolved

Ayahuasca Therapy: Possible Reduction of Suicidal Ideation in Treatment-Resistant Depression - A Systematic Review

Mano-Sousa BJ, Fontes MCG, Gonçalves ACA et al.
Journal of psychoactive drugs, 2026
Systematic review
Clinical Trials
DOI Resolved

Ayahuasca and Its Main Component N,N-Dimethyltryptamine (DMT) for the Treatment of Mental Disorders: Mechanisms of Action, Clinical Studies, and Tools to Explore the Human Mind

Melani A, Papini G, Bonaso M et al.
Biomedicines, 2026
Open Access
Pharmacokinetic study
Depression & Mood
PubMed Verified

A quantitative textual analysis of the subjective effects of ayahuasca in naive users with and without depression

Cruz L, Bienemann B, Palhano-Fontes F et al.
Scientific Reports, 2023
10 citationsOpen Access
Cross-sectional survey
Clinical Trials
PubMed Verified

Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial

Palhano-Fontes F, Barreto D, Onias H et al.
Psychological Medicine, 2019
500 citationsOpen Access
Randomized Controlled Trial
Depression & Mood
PubMed Verified

Cortisol modulation by ayahuasca in patients with treatment resistant depression and healthy controls

Galvao ACM, de Almeida RN, Silva EAS et al.
Frontiers in Psychiatry, 2018
90 citationsOpen Access
Secondary analysis of RCT
Reviews
PubMed Verified

Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and LSD: a systematic review of clinical trials published in the last 25 years

Dos Santos RG, Osorio FL, Crippa JAS et al.
Therapeutic Advances in Psychopharmacology, 2016
350 citationsOpen Access
Systematic review