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NeurosciencePubMed Verified

Long-term use of psychedelic drugs is associated with differences in brain structure and personality in humans

Bouso JC, Palhano-Fontes F, Rodriguez-Fornells A, Ribeiro S, Sanches R, Crippa JAS, Hallak JEC, de Araujo DB, Riba J

European Neuropsychopharmacology (2015)

Cross-sectional survey
Abstract

MRI study comparing 22 long-term ayahuasca users vs 22 matched controls. Found cortical thinning in posterior cingulate cortex correlated with duration of use, and personality differences in harm avoidance and self-transcendence.

Participants44
Citations220
Study TypeCross-sectional survey
MRIcortical thicknesspersonalitylong-term use
DOI: 10.1016/j.euroneuro.2015.01.008View on PubMed

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