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NeurosciencePubMed VerifiedOpen Access

The psychedelic state induced by ayahuasca modulates the activity and connectivity of the default mode network

Palhano-Fontes F, Andrade KC, Tofoli LF, Santos AC, Crippa JA, Hallak JE, Ribeiro S, de Araujo DB

PLOS ONE (2015)

Neuroimaging study
Abstract

fMRI study showing ayahuasca significantly reduces Default Mode Network activity and connectivity, including posterior cingulate cortex and medial prefrontal cortex. Consistent with the entropic brain hypothesis.

Participants10
Citations350
Study TypeNeuroimaging study
fMRIdefault mode networkfunctional connectivity
DOI: 10.1371/journal.pone.0118143View on PubMed

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