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6 results for “dose-dependent”
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Pharmacology
PubMed Verified

Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: a factorial dose-escalation study

Egger K, Jareno Redondo J, Mueller J et al.
Biomedicine & Pharmacotherapy, 2025
5 citationsOpen Access
Randomized controlled trial
Clinical Trials
PubMed Verified

Acute experiences and persisting psychological effects associated with an encapsulated DMT-harmala alkaloid combination: results of a phase 1 study

Perkins D, Halman A, Urokohara A et al.
Scientific Reports, 2025
Open Access
Phase 1 trial
Pharmacology
PubMed Verified

Human pharmacology of ayahuasca: subjective and cardiovascular effects, monoamine metabolite excretion, and pharmacokinetics

Riba J, Valle M, Urbano G et al.
Journal of Pharmacology and Experimental Therapeutics, 2003
500 citations
Double-blind placebo-controlled
Safety
PubMed Verified

Evaluation of the cytotoxicity of ayahuasca beverages

Simao AY, Goncalves J, Gradillas A et al.
Molecules, 2020
20 citationsOpen Access
Preclinical in vitro
Safety
PubMed Verified

Maternal and developmental toxicity of the hallucinogenic plant-based beverage ayahuasca in rats

da Motta LG, de Morais JA, Tavares JF et al.
Reproductive Toxicology, 2018
40 citations
Preclinical in vivo
Pharmacology
PubMed Verified

Human psychopharmacology of N,N-dimethyltryptamine

Strassman RJ
Behavioural Brain Research, 1996
550 citations
Randomized Controlled Trial