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PharmacologyPubMed VerifiedOpen Access

The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen ayahuasca, stimulate adult neurogenesis in vitro

Morales-Garcia JA, de la Fuente Revenga M, Alonso-Gil S, Rodriguez-Franco MI, Feilding A, Perez-Castillo A, Riba J

Scientific Reports (2017)

Preclinical / in vitro
Abstract

Found that harmine, harmaline, and THH from B. caapi stimulate proliferation and differentiation of adult neural progenitor cells in vitro. First evidence that the beta-carboline alkaloids themselves promote neurogenesis.

Citations190
Study TypePreclinical / in vitro
neurogenesisharmineharmalineneural progenitors
DOI: 10.1038/s41598-017-05407-9View on PubMed

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